Product Description: Nebivolol (hydrochloride) (Standard) is the analytical standard of Nebivolol (hydrochloride). This product is intended for research and analytical applications. Nebivolol (R 065824) hydrochloride is an orally active beta receptor blocker and has the high beta(1)-receptor affinity.Nebivolol hydrochloride has direct vasodilator properties and adrenergic blocking characteristics. Nebivolol hydrochloride can be used for the research of kinds of diseases such as hypertension, coronary artery disease, congestive heart failure and ischemic heart disease[1][2].
Formula: C22H26ClF2NO4
References: [1]Brehm BR, et al. Effects of nebivolol on proliferation and apoptosis of human coronary artery smooth muscle and endothelial cells. Cardiovasc Res. 2001 Feb 1;49(2):430-9./[2]Thomas Münzel, et al. Nebivolol: the somewhat-different beta-adrenergic receptor blocker. J Am Coll Cardiol. 2009 Oct 13;54(16):1491-9.
CAS Number: 152520-56-4
Molecular Weight: 441.90
Research Area: Cardiovascular Disease; Endocrinology
Solubility: DMSO : 100 mg/mL (ultrasonic)/H2O : 1.79 mg/mL (ultrasonic;warming;heat to 60°C)
Target: Adrenergic Receptor
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