Product Description: pan-KRAS-IN-2 (compound 6) is a pan inhibitor of with IC50s ≤10 nM for KRAS WT and mutants (G12D, G12C, G12V, G12S, G12A, Q61H), and >10 μM for KRAS G13D, respectively[1].
Applications: Cancer-Kinase/protease
Formula: C34H34F2N4O3
References: [1]Jones C, et al. Quinazoline derivatives useful as Ras inhibitors and their preparation. World Intellectual Property Organization, WO2022258974 A1. 2022-12-15.
CAS Number: 2882825-14-9
Molecular Weight: 584.66
Compound Purity: 98.01
Research Area: Cancer
Solubility: DMSO : 125 mg/mL (ultrasonic)
Target: Ras