pan-KRAS-IN-5, CAS 3027172-23-9

Product Description: pan-KRAS-IN-5 (compound 15a) is a pan-KRAS translation inhibitor by targeting 5′-UTR RNA G-quadruplexes (rG4s). pan-KRAS-IN-5 induces cell cycle arrest and promptes apoptosis in KRAS-driven cancer cells[1].

Applications: Cancer-Kinase/protease

Formula: C31H36FIN4O2

References: [1]Mao-Lin Li, et al. Discovery of Novel Coumarin-quinolinium Derivatives as Pan-KRAS Translation Inhibitors by Targeting 5'-UTR RNA G-Quadruplexes. J Med Chem. 2024 Feb 8;67(3):1961-1981.

CAS Number: 3027172-23-9

Molecular Weight: 642.55

Compound Purity: 90.0

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Apoptosis;Ras

• SKU: MEXHY-163299-50
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-163299-50
• Package Unit: 50 mg
• Quantity Unit: STK