PAR3 (1-6) (human), CAS 320347-28-2

Product Description: PAR3 (1-6) is a synthetic peptide agonist of proteinase-activated receptor 1 (PAR1) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of human PAR3 and residues 39-44 of the full-length human sequence. PAR3 (1-6) activates p42/44 MAPK signaling in fibroblasts expressing PAR1, but not PAR3, an effect that can be blocked by the PAR1 antagonist RWJ 56110.

Applications: COVID-19-immunoregulation

Formula: C29H45N9O8

References: [1]Kaufmann, et al. Proteinase-activated receptors (PARs) - The PAR3 neo-N-terminal peptide TFRGAP interacts with PAR1. Regul. Pept. 125(1-3), 61-66 (2005).

CAS Number: 320347-28-2

Molecular Weight: 647.72

Research Area: Inflammation/Immunology

Target: Protease Activated Receptor (PAR)

• SKU: MEXHY-P2380-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P2380-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK