Product Description: Pardoprunox (SLV-308) hydrochloride is a partial dopamine D2 and D3 receptor partial agonist and a serotonin 5-HT1A receptor agonist, with pEC50s of 8, 9.2, and 6.3, respectively[1].
Applications: Neuroscience-Neuromodulation
Formula: C12H16ClN3O2
References: [1]Glennon JC, et al. In vitro characterization of SLV308 (7-[4-methyl-1-piperazinyl]-2(3H)-benzoxazolone, monohydrochloride): a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist. Synapse. 2006 Dec 15;60(8):599-608./[2]Jones CA, et al. An in vivo pharmacological evaluation of pardoprunox (SLV308)--a novel combined dopamine D(2)/D(3) receptor partial agonist and 5-HT(1A) receptor agonist with efficacy in experimental models of Parkinson's disease. Eur Neuropsychopharmacol. 2010 Aug;20(8):582-593.
CAS Number: 269718-83-4
Molecular Weight: 269.73
Compound Purity: 98.89
Research Area: Neurological Disease; Endocrinology
Solubility: DMSO : 150 mg/mL (ultrasonic)/H2O : 25 mg/mL (ultrasonic)
Target: 5-HT Receptor;Adrenergic Receptor;Dopamine Receptor
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