Product Description: PD-168077 is a selective dopamine D4 receptor agonist, with a Ki of 9 nM[1].
Applications: Neuroscience-Neuromodulation
Formula: C20H22N4O
References: [1]Clifford JJ, et al. Topographically based search for an "Ethogram" among a series of novel D(4) dopamine receptor agonists and antagonists. Neuropsychopharmacology. 2000 May;22(5):538-44./[2]Gu Z, et al. Activation of dopamine D4 receptors induces synaptic translocation of Ca2+/calmodulin-dependent protein kinase II in cultured prefrontal cortical neurons. Mol Pharmacol. 2006 Mar;69(3):813-22.