PDGFRα kinase inhibitor 2, CAS 404844-11-7

Product Description: PDGFRα kinase inhibitor 2 (compound 1), an Imatinib (HY-15463) analogue, is a covalent and irreversible kinase inhibitor with IC50s of 6.95 μM, 2.45 μM, 1.39 μM for ABL1 wt, KIT wt, PDGFRR wt[1].

Formula: C24H20ClN5O

References: [1]Emeline Leproult, et al. Cysteine mapping in conformationally distinct kinase nucleotide binding sites: application to the design of selective covalent inhibitors. J Med Chem. 2011 Mar 10;54(5):1347-55.

CAS Number: 404844-11-7

Molecular Weight: 429.90

Compound Purity: 98.0

Research Area: Cancer

Target: Bcr-Abl;c-Kit;PDGFR

• SKU: MEXHY-W143698-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W143698-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK