PROTAC EGFR degrader 11, CAS 3034244-71-5

Product Description: PROTAC EGFR degrader 11 (Compound B71) is a PROTAC degrader for epidermal growth factor receptor (EGFR), with DC50 Ki of 36 nM. PROTAC EGFR degrader 11 degrades EGFR, focal adhesion kinase (FAK), and RSK1, inhibits the proliferation of BaF3 wild type and EGFR mutants, with IC50 <100 nM.

Applications: Cancer-Kinase/protease

Formula: C49H64ClFN10O7S

References: [1]Han W, et al., Compound for targeted protein degradation, and use thereof. WO2024072178A1

CAS Number: 3034244-71-5

Molecular Weight: 991.61

Research Area: Cancer

Target: EGFR;FAK;PROTACs

• SKU: MEXHY-161633-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-161633-0
• Package Unit: Get quote
• Quantity Unit: STK