Product Description: PW0729 (compound 15b) is an orphan GPR52 agonist with potential applications in GPR52 activation, signaling bias, and neuropsychiatric and neurological disorders. The brain exposure characteristics of PW0729 need to be further optimized[1].
Formula: C23H22F3N3O2
References: [1]Murphy R E, Wang P, Ali S, et al. Discovery of 3-((4-Benzylpyridin-2-yl) amino) benzamides as Potent GPR52 G Protein-Biased Agonists[J]. Journal of Medicinal Chemistry, 2024.
CAS Number: 2767348-36-5
Molecular Weight: 429.43
Research Area: Neurological Disease
Target: GPR52