Product Description: RTDLDSLRTYTL is an Alpha (v) beta (6) integrin (avb6) inhibitor with high affinity and specificity. RTDLDSLRTYTL binds to avb6 integrin, a peptide sequence that activates cytotoxicity and cytokine production in T cells, such as interferon-gamma. RTDLDSLRTYTL is designed through a chimeric T cell antigen receptor (CAR) so that T cells can be redirected to specifically recognize and attack tumor cells. RTDLDSLRTYTL can be used in the research of cancer immunotherapy and targeted drug development[1].
Applications: Cancer-programmed cell death
Formula: C62H104N18O22
References: [1]Pameijer C R J, et al. Conversion of a tumor-binding peptide identified by phage display to a functional chimeric T cell antigen receptor[J]. Cancer gene therapy, 2007, 14(1): 91-97.
CAS Number: 222557-93-9
Molecular Weight: 1453.60
Research Area: Cancer; Others
Target: Integrin
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