Product Description: Rusfertide is a peptide mimetic of natural hepcidin, which targets and degrades ferroportin, reduces serum iron and transferrin-saturation, and thus regulates the production of red blood cells. Rusfertide ameliorates the polycythemia vera, β-thalassemia and hereditary hemochromatosis[1][2].
Applications: Neuroscience-Neuromodulation
Formula: C114H181N27O28S2
References: [1]Taranath R, et al., Regulation of iron homeostasis by PTG-300 improves disease parameters in mouse models for beta-thalassemia and hereditary hemochromatosis[J]. Blood, 2019, 134: 3540./[2]Kremyanskaya M, et al., PTG-300 eliminates the need for therapeutic phlebotomy in both low and high-risk polycythemia vera patients[J]. Blood, 2020, 136: 33-35.
CAS Number: 1628323-80-7
Molecular Weight: 2441.95
Compound Purity: 96.69
Research Area: Others
Solubility: DMSO : ≥ 100 mg/mL
Target: Ferroportin
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