Product Description: SCR-1481B1 free base, also known as Metatinib free base, is a small molecule receptor kinase inhibitor that targets both c-MET and vascular endothelial growth factor receptor 2 (VEGFR2)[1].
Applications: Cancer-Kinase/protease
Formula: C24H18ClF2N4O7P
References: [1]Cheng K, et al. Safety, Efficacy, and Pharmacokinetics of Metatinib Tromethamine Tablet in Patients with Advanced Refractory Solid Tumors: A Phase I Clinical Trial. Oncologist. 2021 Aug;26(8):649-e1313.
CAS Number: 1174161-69-3
Molecular Weight: 578.85
Research Area: cancer
Target: c-Met/HGFR;VEGFR