SHBG(141–161)

Product Description: SHBG 141-161 is a GPRC6A receptor agonist. SHBG 141-161 mimics the action of GPRC6A endogenous agonist uncarboxylated osteocalcin by binding to GPRC6A and promoting downstream signaling to increase testosterone and insulin secretion. SHBG 141-161 also reduces the affinity of GPRC6A to GDP protein by binding to the outer cell domain of GPRC6A thus affecting the dynamics of signal transduction. SHBG 141-161 can be used to study GPRC6A in energy metabolism and endocrine regulation[1].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C103H173N25O24

References: [1]De Toni L, et al. SHBG141–161 domain-peptide stimulates GPRC6A-mediated response in leydig and β-Langerhans cell lines[J]. Scientific Reports, 2019, 9(1): 19432.

Molecular Weight: 2145.63

Research Area: Endocrinology; Metabolic Disease

Target: Androgen Receptor

• SKU: MEXHY-P10413-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P10413-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK