SLF80821178 (hydrochloride), CAS 2764877-62-3

Product Description: SLF80821178 hydrochloride is an orally active inhibitor for sphingosine-1-phosphate transporter (Spns2), that inhibits the sphingosine-1-phosphate (S1P) release in HeLa with an IC50 of 51 nM. SLF80821178 hydrochloride reduces the circulating lymphocyte without affecting plasma S1P levels in mice[1].

Applications: COVID-19-immunoregulation

Formula: C21H36ClN3O

References: [1]Foster DJ, et al., Discovery of Potent, Orally Bioavailable Sphingosine-1-Phosphate Transporter (Spns2) Inhibitors. J Med Chem. 2024 Jul 11;67(13):11273-11295.

CAS Number: 2764877-62-3

Molecular Weight: 381.98

Research Area: Inflammation/Immunology

Target: LPL Receptor

• SKU: MEXHY-162655A-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-162655A-0
• Package Unit: Get quote
• Quantity Unit: STK