Tat-AKAP79 (326-336)

Product Description: TAT-AKAP79 326-336 is a cytoosmotic peptide. TAT-AKAP79 326-336 mimics a specific region on the AKAP79 protein that binds to TRPV1 ion channels (amino acid sequence 326-336). TAT-AKAP79 326-336 inhibits the sensitization of TRPV1 and reduce the overresponse of TRPV1 channels to stimuli caused by the activation of cellular kinases such as protein kinase A (PKA) and protein kinase C (PKC) by inflammatory mediators. TAT-AKAP79 326-336 can be used to study the mechanism of pain transduction and inflammatory hyperalgesia[1].

Applications: COVID-19-immunoregulation

Formula: C117H211N49O34S

References: [1]Btesh J, et al. Mapping the binding site of TRPV1 on AKAP79: implications for inflammatory hyperalgesia[J]. Journal of Neuroscience, 2013, 33(21): 9184-9193.

Molecular Weight: 2880.30

Research Area: Inflammation/Immunology; Neurological Disease

Target: TRP Channel

• SKU: MEXHY-P10464-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P10464-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK