Tat-braftide

Product Description: Tat-braftide is a peptide inhibitor designed to block the dimerization of BRAF, thereby inhibiting its kinase activity. The destruction of BRAF dimer by Tat-braftide makes BRAF protein more susceptible to proteasome degradation, directly inhibits the activity of BRAF kinase, and reduces the activation of MAPK signaling pathway. Tat-braftide can be used for the role of RAF kinase in MAPK signaling pathway and for the study of BRAF mutant cancers[1].

Applications: Cancer-Kinase/protease

Formula: C128H227N51O30S

References: [1]Gunderwala A Y, et al. Development of allosteric BRAF peptide inhibitors targeting the dimer interface of BRAF[J]. ACS chemical biology, 2019, 14(7): 1471-1480.

Molecular Weight: 2992.56

Research Area: Cancer

Target: Raf

• SKU: MEXHY-P10438-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P10438-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK