Product Description: TAT-D1 peptide is a selective D1-D2 heterogeneous antagonist. TAT-D1 peptide destroys the heterodimer of the D1-D2 receptor by interacting with the specific domain of the D2 receptor through its unique amino acid sequence, in particular the two glutamate residues at the C terminal of the D1 receptor. TAT-D1 peptide can be used to study the role of D1-D2 receptor heterodimers in the regulation of depressive and anxiety-like behaviors[1].
Applications: Neuroscience-Neuromodulation
Formula: C144H257N57O43
References: [1]Shen M Y F, et al. Rapid anti-depressant and anxiolytic actions following dopamine D1–D2 receptor heteromer inactivation[J]. European Neuropsychopharmacology, 2015, 25(12): 2437-2448.
Molecular Weight: 3474.94
Research Area: Neurological Disease
Target: Dopamine Receptor