Product Description: Telenzepine dihydrochloride is a selective and orally active muscarinic M1 receptor antagonist with a Ki of 0.94 nM. Telenzepine dihydrochloride inhibits gastric acid secretion and has antiulcer effects[1][2][3].
Applications: Neuroscience-Neuromodulation
Formula: C19H24Cl2N4O2S
References: [1]R Riedel, et al. Comparison of the gastric antisecretory and antiulcer potencies of telenzepine, pirenzepine, ranitidine and cimetidine in the rat. Digestion. 1988;40(1):25-32./[2]F L Christofi, et al. Neuropharmacology of the muscarinic antagonist telenzepine in myenteric ganglia of the guinea-pig small intestine. Eur J Pharmacol. 1991 Apr 3;195(3):333-9./[3]M Galvan, et al. Interaction of telenzepine with muscarinic receptors in mammalian sympathetic ganglia. Eur J Pharmacol. 1989 Aug 11;167(1):1-10.
CAS Number: 147416-96-4
Molecular Weight: 443.39
Compound Purity: 99.08
Research Area: Neurological Disease
Solubility: H2O : 62.5 mg/mL (ultrasonic;warming;heat to 60°C)
Target: mAChR
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