Product Description: Terodiline, an antispasmodic agent, blocks hERG current with the IC50 of 375 nM.?Terodiline has both anticholinergic and calcium antagonist properties, and effectively reduces abnormal bladder contractions caused by detrusor instability.?Terodiline can be used for the research of urinary incontinence[1][2].
Applications: Neuroscience-Neuromodulation
Formula: C20H27N
References: [1]Ruth L Martin, et al. In vitro preclinical cardiac assessment of tolterodine and terodiline: multiple factors predict the clinical experience. J Cardiovasc Pharmacol. 2006 Nov;48(5):199-206./[2]H D Langtry, et al. Terodiline. A review of its pharmacological properties, and therapeutic use in the treatment of urinary incontinence. Drugs. 1990 Nov;40(5):748-61.
CAS Number: 15793-40-5
Molecular Weight: 281.44
Research Area: Metabolic Disease
Solubility: 10 mM in DMSO
Target: Calcium Channel;mAChR;Potassium Channel
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