Product Description: TNFAIP8 Protein functions as a negative regulator of apoptosis, inhibiting caspase-8 activity and suppressing TNF-mediated apoptosis without affecting procaspase-8 processing. This control prevents BID cleavage and subsequent caspase-3 activation, contributing to cellular survival mechanisms. TNFAIP8's role highlights its potential significance in apoptosis regulation and its implications for tumor development. TNFAIP8 Protein, Human (His) is the recombinant human-derived TNFAIP8 protein, expressed by E. coli , with N-His labeled tag.
Formula: 25816(Gene_ID)O95379-1 (M1-I198)(Accession)
Molecular Weight: Approximately 24 kDa
Compound Purity: 97.00