Tregitope 289

Tregitope 289
SKU
MEXHY-P10492-0
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MedChemExpress

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Product Description: Tregitope 289 is a peptide derived from the Fc region of immunoglobulin G (IgG) and is a highly conserved T cell epitope that stimulates the expansion of natural regulatory T cells. Co-delivery of Tregitope 289 with type 1 diabetes (T1D) antigens delays the development of hyperglycemia and reduces the incidence of diabetes in the NOD mouse model. Tregitope 289 can be used to study T1D and other autoimmune diseases[1].

Formula: C115H173N31O36

References: [1]Cousens L P, et al. Application of IgG‐derived natural Treg epitopes (IgG Tregitopes) to antigen‐specific tolerance induction in a murine model of type 1 diabetes[J]. Journal of diabetes research, 2013, 2013(1): 621693.

Molecular Weight: 2565.79

Research Area: Metabolic Disease; Others

Target: Others
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SKU MEXHY-P10492-0
Manufacturer MedChemExpress
Manufacturer SKU HY-P10492-0
Green Labware No
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