Product Description: TRPV1-Tat is an antagonistic peptide that fuses the TRPV1 (transient receptor potential vanilla subtype 1) of the cell-penetrating peptide Tat. TRPV1-Tat blocks this phosphorylation process by competitively binding to the AKAP79 binding site of TRPV1, thereby inhibiting the sensitization of TRPV1. TRPV1-Tat can be used in the study of inflammatory pain[1].
Applications: COVID-19-immunoregulation
Formula: C127H206N50O29S
References: [1]Fischer M J M, et al. Disrupting sensitization of transient receptor potential vanilloid subtype 1 inhibits inflammatory hyperalgesia[J]. Journal of Neuroscience, 2013, 33(17): 7407-7414.
Molecular Weight: 2929.38
Research Area: Inflammation/Immunology
Target: TRP Channel