Product Description: Tyk2-IN-18 (compound 86) is a potent tyrosine kinase 2 (Tyk2) inhibitor. Tyk2-IN-18 inhibits JAK2-JH2, with an IC50 of [1][2].
Applications: Cancer-Kinase/protease
Formula: C21H24F2N4O3
References: [1]Ram W. Sabnis. Novel Tyrosine Kinase 2 Inhibitors for Treating Autoimmune and Inflammatory Diseases. ACS Med. Chem. Lett. May 16, 2024./[2]Jeffrey Vessels, et al. Tyrosine kinase 2 inhibitors and uses thereof. WO2023250064A1. 2023-12-28.