Vapitadine (hydrochloride), CAS 279253-83-7

Product Description: Vapitadine hydrochloride (Compound 3a) is a selective, orally active and nonsedating antihistamine agent, which exhibits a good binding affinity with human cloned histamine H1 receptor with a Ki of 19 nM. Vapitadine hydrochloride decreases the histamine-induced lethality (ED50 is 0.056-1.2 mg/kg), antagonizes the cutaneous reactions to histamine (ED50 is 0.51-1.4 mg/kg) in rats[1].

Applications: COVID-19-immunoregulation

Formula: C17H22Cl2N4O

References: [1]Janssens F, et al., Norpiperidine imidazoazepines as a new class of potent, selective, and nonsedative H1 antihistamines. J Med Chem. 2005 Mar 24;48(6):2154-66.

CAS Number: 279253-83-7

Molecular Weight: 369.29

Research Area: Inflammation/Immunology

Target: Histamine Receptor

• SKU: MEXHY-14939A-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-14939A-0
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• Quantity Unit: STK