VEGFR-2-IN-47

Product Description: VEGFR-2-IN-47 (compound 7g) is a potent VEGFR-2 inhibitor with an IC50 value of 0.072 µM. VEGFR-2-IN-47 can induce G2 / M phase cell cycle arrest, promote apoptosis, and boost immunomodulation by downregulating TNF-α expression and upregulating IL-2 levels in MCF-7 cells. VEGFR-2-IN-47 has the potential to be used for the research of cancer such as breast cancer and liver carcinoma [1].

Applications: Cancer-Kinase/protease

Formula: C23H22N6O4

References: [1]Jingyi Liu, et al. Identification of 3-(9H-carbazol-9-yl)-2-(1,3-dioxoisoindolin-2-yl)propanoic acids as promising DNMT1 inhibitors. Eur J Med Chem. 2024 Aug 5;274:116538.

Molecular Weight: 446.46

Target: VEGFR

• SKU: MEXHY-163747-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-163747-0
• Package Unit: Get quote
• Quantity Unit: STK