VEGFR-2-IN-50

Product Description: VEGFR-2-IN-50 (Compound 10f) is a VEGFR-2 inhibitor and apoptosis inducer, with an IC50 value of 0.33 μM. VEGFR-2-IN-50 (Compound 10f) has growth inhibitory activity on MCF-7 and MDA-MB-231 breast cancer cell lines, with IC50 values of 19.86 μM and 10.88 μM, respectively, which is expected to be used in the study of breast cancer diseases[1].

Formula: C23H16BrN5O

References: [1]Mahmoud S. Elkotamy, et al. Novel imidazo[2,1-b]thiazoles and imidazo[1,2-a]pyridines tethered with indolinone motif as VEGFR-2 inhibitors and apoptotic inducers: Design, synthesis and biological evaluations. Bioorganic Chemistry. 2024 Oct; 151: 107644.

Molecular Weight: 458.31

Research Area: Cancer

Target: Apoptosis;VEGFR

• SKU: MEXHY-161855-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-161855-0
• Package Unit: Get quote
• Quantity Unit: STK