Product Description: VGB4 is a VEGF-A and VEGF-B antagonist peptide that duplicates two binding domains of VEGF-B (loop 1 and loop3) and are linked together by the receptor-binding domain of VEGF-A (loop3). VGB4 has significant anti-angiogenic and anti-tumor activities and can regulate tumor growth and metastasis through multiple mechanisms. VGB4 could be used in anti-tumor research[1].
Formula: C122H205N33O32S2
References: [1]Farzaneh Behelgardi M, et al. A peptide mimicking the binding sites of VEGF-A and VEGF-B inhibits VEGFR-1/-2 driven angiogenesis, tumor growth and metastasis[J]. Scientific reports, 2018, 8(1): 17924.
Molecular Weight: 2710.27
Research Area: Cancer
Target: VEGFR