xStAx-VHLL

Product Description: xStAx-VHLL is a PROTAC β-catenin degrader that manifests strong inhibition of Wnt signaling and sustains degradation of β-catenin in cancer cells and the intestinal organoids derived from wild-type and APC–/– mice. xStAx-VHLL can be used as a promising anticancer agent[1].

Applications: Cancer-programmed cell death

Formula: C154H244N48O29

References: [1]Liao H, et al. A PROTAC peptide induces durable β-catenin degradation and suppresses Wnt-dependent intestinal cancer. Cell Discov. 2020 Jun 9;6:35.

Molecular Weight: 3231.89

Compound Purity: 99.37

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: APC;PROTACs;Wnt;β-catenin

• SKU: MEXHY-P5819-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P5819-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK