Product Description: YS-363 is a potent, selective, and orally active EGFR inhibitor, with IC50s of 0.96 nM and 0.67 nM for wild-type and L858R mutant forms of EGFR, respectively. YS-363 can induce G0/G1 cell cycle arrest and apoptosis[1].
Applications: Cancer-Kinase/protease
Formula: C30H30N4O3
References: [1]He P, et, al. Discovery of YS-363 as a highly potent, selective, and orally efficacious EGFR inhibitor. Biomed Pharmacother. 2023 Nov:167:115491.
CAS Number: 2470908-90-6
Molecular Weight: 494.58
Compound Purity: 99.52
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Apoptosis;EGFR