Formulation: A solid
Formal Name: 2α,3β,19-trihydroxy-urs-12-en-28-oic acid, β-D-glucopyranosyl ester
Purity: ≥98%
Formula Markup: C36H58O10
Formula Weight: 650,8
Shelf life (days): 1460
CAS Number: 88515-58-6
Notes: Rosamultin is a triterpenoid glycoside that has been found in R. rugosa and has diverse biological activities.{66720,66721,66722,66723} It inhibits HIV-1 protease by 52.9% in a cell-free assay when used at a concentration of 100 µM.{66720} Rosamultin (0.01 nM) reduces hydrogen peroxide-induced apoptosis, increases in malondialdehyde (MDA) levels, and decreases in superoxide dismutase (Sod), catalase (Cat), and glutathione peroxidase (Gpx) activities in H9c2 rat cardiomyocytes.{66721} In vivo, rosamultin (12 mg/kg) increases survival, prevents decreases in body weight, and protects against splenic and intestinal damage in irradiated mice.{66722} Rosamultin (30 mg/kg, p.o.) inhibits acetic acid-induced writhing in mice.{66723}
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