Formulation: A solution in water
Formal Name: 2' or 3′-(2-aminobenzoate)guanosine 5′-(tetrahydrogen triphosphate), tetrasodium salt
Purity: ≥95% (mixture of isomers)
Formula Markup: C17H17N6O15P3 • 4Na
Formula Weight: 730,2
Shelf life (days): 730
Notes: 2'(3')-O-Anthraniloylguanosine-5'-O-triphosphate (2'-ANT-GTP) and 3'-ANT-GTP are fluorescent GTP derivatives, which undergo spontaneous isomerization.{65690} 2'(3')-ANT-GTP displays an emission maximum of 428 nm upon excitation at 330 nm in water.{67581} It inhibits mammalian adenylyl cyclase 1 (AC1; Ki = 10 nM in the presence of manganese), B. anthracis AC toxin edema factor (Kis = 4.1 and 13 µM in the presence of manganese and magnesium, respectively), and B. pertussis AC toxin CyaA (Ki = 29 µM in the presence of manganese).{65690,65692,65691}