2-TEDC, CAS 132465-10-2

Formulation: A solid

Formal Name: 2-cyano-3-(3,4-dihydroxyphenyl)-2-propenoic acid, 2-(2-thienyl) ethyl ester

Purity: ≥98%

Formula Markup: C16H13NO4S

Formula Weight: 315,3

Shelf life (days): 1460

CAS Number: 132465-10-2

Notes: 2-TEDC is a lipoxygenase (LO) inhibitor (IC50s = 0.09, 0.013, and 0.5 µM for 5-, 12-, and 15-LO, respectively).{68} It prevents axon degeneration induced by withdrawal of nerve growth factor (NGF) in primary rat dorsal root ganglion neurons (mean EC50 = 2.79 µM).{66934} 2-TEDC also inhibits severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA-dependent RNA polymerase (RdRp; IC50 = 7.99 µM) and reduces major capsid protein levels and virus titers in grouper spleen cells infected with Singapore grouper iridovirus when used at a concentration of 12.5 µM.{66935,66936}

• SKU: CAY41872-100
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 41872-100
• Package Unit: 100 mg
• Quantity Unit: STK