3-Deazaneplanocin A (hydrochloride) (GMP), CAS 120964-45-6

Product Description: 3-Deazaneplanocin A (DZNep) hydrochloride (GMP) is 3-Deazaneplanocin A hydrochloride (HY-12186) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. 3-Deazaneplanocin A hydrochloride is a potent histone methyltransferase EZH2 inhibitor[1][2].

Applications: COVID-19-immunoregulation

Formula: C12H15ClN4O3

References: [1]Hou P, et al. Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds. Science. 2013 Aug 9;341(6146):651-4. /[2]Zhao C, et al. DZNep and UNC0642 enhance in vitro developmental competence of cloned pig embryos. Reproduction. 2018 Apr 1;157(4):359-369. /[3]Fiskus W, et al. Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cells. Blood. 2009 Sep 24;114(13):2733-43.

CAS Number: 120964-45-6

Molecular Weight: 298.73

Research Area: Cancer; Infection

Solubility: 10 mM in DMSO

Target: Histone Methyltransferase;Orthopoxvirus

• SKU: MEXHY-12186G-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-12186G-0
• Package Unit: Get quote
• Quantity Unit: STK