33-BCRP Inhibitor

Formulation: A solid

Formal Name: N-(4-azidophenyl)-2-(pyridin-4-yl)quinazolin-4-amine

Purity: ≥98%

Formula Markup: C19H13N7

Formula Weight: 339,4

Shelf life (days): 730

Notes: 33-BCRP inhibitor is an inhibitor of breast cancer resistance protein (BCRP).{67491} It sensitizes mitoxantrone-resistant H460/MX20 lung cancer cells to mitoxantrone-induced cell death alone and in combination with UV radiation. 33-BCRP inhibitor also sensitizes KB-C2 epidermal carcinoma cells overexpressing P-glycoprotein (P-gp), also known as multidrug resistance protein (MDR), to colchicine-induced cell death. It increases intracellular accumulation of mitoxantrone (Item No. 14842) in H460/MX20 cells when used at a concentration of 5 µM.

• SKU: CAY39403-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 39403-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK