4,5,6,7-Tetrabromobenzimidazole, CAS 577779-57-8

Formulation: A crystalline solid

Formal Name: 4,​5,​6,​7-​tetrabromo-1H-​benzimidazole

Purity: ≥98%

Formula Markup: C7H2Br4N2

Formula Weight: 433,7

Shelf life (days): 1460

CAS Number: 577779-57-8

Notes: Casein kinase 2 (CK2) is a constitutive protein kinase involved in many signal transduction pathways. CK2 is known to negatively regulate apoptosis, and its activity is increased in many proliferating tissues and tumors. 4,5,6,7-Tetrabromobenzimidazole is a selective, ATP-competitive inhibitor of CK2 with Ki values ranging from 0.5-1 µM in rat liver, S. cerevisiae, C. tropicalis, and N. crassa.{30429} It is inactive against PKA and PKC and a relatively weak inhibitor of CK1 (Ki = 54.4-64.2 µM).{30429}

• SKU: CAY18886-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 18886-10
• Package Unit: 10 mg
• Quantity Unit: STK