Formulation: A solid
Formal Name: 5,7-dimethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
Purity: ≥98%
Formula Markup: C18H16O5
Formula Weight: 312,3
Shelf life (days): 1460
CAS Number: 5631-70-9
Notes: 4’,5,7-Trimethoxyflavone is a flavonoid that has been found in K. parviflora and has diverse biological activities.{72278,67058,72279} It inhibits acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) by 47.1 and 46.2%, respectively, in a cell-free assay when used at a concentration of 0.1 mg/ml.{72278} 4’,5,7-Trimethoxyflavone (1 and 10 µM) scavenges radicals in a Trolox equivalent antioxidant capacity (TEAC) assay.{67058} It inhibits RANKL-induced osteoclastic differentiation of RAW 264.7 cells when used at a concentration of 10 µM. 4’,5,7-Trimethoxyflavone stimulates chloride secretion in Calu-3 human airway epithelial cells, which endogenously express cystic fibrosis transmembrane conductance regulator (CFTR) as their major apical chloride channel.{72279}
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