4-hydroxy Diclofenac, CAS 64118-84-9

Formulation: A crystalline solid

Formal Name: 2-[(2,6-dichloro-4'-hydroxyphenyl)amino]-benzeneacetic acid

Purity: ≥95%

Formula Markup: C14H11Cl2NO3

Formula Weight: 312,2

Shelf life (days): 1460

CAS Number: 64118-84-9

Notes: 4-hydroxy Diclofenac is an active metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor diclofenac (Item Nos. 70680 / 22983).{14145} It is formed from diclofenac by the cytochrome P450 (CYP) isoform CYP2C9 in human liver microsomes.{65583} 4-hydroxy Diclofenac inhibits COX activity (IC50 = 32 nM) and reduces prostaglandin E2 (PGE2; Item No. 14010) production (IC50 = 17 nM) in isolated human rheumatoid synovial cells.{28498}

• SKU: CAY10008518-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 10008518-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK
• Application: Reinstoffe