4-phenyl-1,2,3-Thiadiazole, CAS 25445-77-6

Formulation: A crystalline solid

Purity: ≥98%

Formula Markup: C8H6N2S

Formula Weight: 162,2

Shelf life (days): 1460

CAS Number: 25445-77-6

Notes: Cytochrome P450 (CYP450) enzymes are a superfamily of oxidative catalysts important in the biosynthesis and metabolism of a wide range of endogenous molecules as well as the metabolism of xenobiotics. For example, CYP2B4 metabolizes substituted amines, CYP2E1 metabolizes various alcohols and halogenated alkenes, and CYP1A2 catalyzes the oxygenation of aromatic compounds and polycyclic hydrocarbons. 4-phenyl-1,2,3-Thiadiazole is, at 100 µM, a selective inhibitor of certain CYP450 enzymes (CYP2B4, CYP2E1), but not others (CYP1A2), with inactivation occurring in a mechanism-based manner.{15950}

• SKU: CAY10011055-250
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 10011055-250
• Green Labware: No
• Package Unit: 250 mg
• Quantity Unit: STK