(5Z,2E)-CU-3, CAS 1815598-71-0

Formulation: A solid

Formal Name: N-[(5Z)-5-[(2E)-3-(2-furanyl)-2-propen-1-ylidene]-4-oxo-2-thioxo-3-thiazolidinyl]-benzenesulfonamide

Purity: ≥98%

Formula Markup: C16H12N2O4S3

Formula Weight: 392,5

Shelf life (days): 1460

CAS Number: 1815598-71-0

Notes: (5Z,2E)-CU-3 is an inhibitor of diacylglycerol kinase α (DGK-α; IC50 = 0.6 µM for the porcine enzyme).{65496} It is selective for DGK-α over other type I DGKs, as well as type II, type III, type IV, and type V DGKs (IC50s = 7-36 µM). (5Z,2E)-CU-3 (5 µM) induces apoptosis in HeLa cervical and HepG2 liver cancer cells and enhances increases in IL2 mRNA expression in Jurkat T cells induced with concanavalin A (Item No. 14951).

• SKU: CAY37770-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 37770-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK
• Application: Reinstoffe