Formulation: A solid
Formal Name: 5-hydroxy-7-methoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
Purity: ≥98%
Formula Markup: C17H14O5
Formula Weight: 298,3
Shelf life (days): 1460
CAS Number: 5128-44-9
Notes: 7,4′-Di-O-methylapigenin is a flavonoid that has been found in T. diffusa and has diverse biological activities.{62624,62625,62626,62627,62628} It inhibits monoamine oxidase B (MAO-B) but not MAO-A (IC50s = 0.198 and >100 µM, respectively), as well as p38α MAPK but not JNK3 (IC50s = 27.8 and >100 µM, respectively).{62624,62625} 7,4′-Di-O-methylapigenin inhibits the production of nitric oxide (NO) in LPS-stimulated RAW 264.7 macrophages (IC50 = 24.5 µM).{62626} It reduces the growth of C. albicans when used at a concentration of 45 µg/ml.{62627} 7,4′-Di-O-methylapigenin inhibits carrageenan-induced edema in rats (ED25 = 75 mg/kg).{62628}
English
Deutsch
