8-Geranyloxypsoralen, CAS 7437-55-0

Formulation: A solid

Formal Name: 9-[[(2E)-3,7-dimethyl-2,6-octadien-1-yl]oxy]-7H-furo[3,2-g][1]benzopyran-7-one

Purity: ≥95%

Formula Markup: C21H22O4

Formula Weight: 338,4

Shelf life (days): 1460

CAS Number: 7437-55-0

Notes: 8-Geranyloxypsoralen is a prenylated furanocoumarin that has been found in C. limon and has diverse biological activities.{9551,69445,21872} It inhibits the cytochrome P450 (CYP) isoform CYP3A4 and β-secretase 1 (BACE1; IC50s = 3.93 and 20.4 µM, respectively).{69445,21872} 8-Geranyloxypsoralen (50 µM) inhibits Epstein-Barr virus activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA; Item No. 10008014) in infected Raji B-lymphoblastoid cells, TPA-induced superoxide generation in HL-60 leukemia cells, and LPS- and IFN-γ-induced nitric oxide (NO) generation in RAW 264.7 macrophages.{9551}

• SKU: CAY35167-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 35167-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK