A-196, CAS 1982372-88-2

Formulation: A crystalline solid

Formal Name: 6,7-dichloro-N-cyclopentyl-4-(4-pyridinyl)-1-phthalazinamine

Purity: ≥98%

Formula Markup: C18H16Cl2N4

Formula Weight: 359,3

Shelf life (days): 1460

CAS Number: 1982372-88-2

Notes: A-196 is a selective inhibitor of SUV420H1 and SUV420H2 (IC50s = 25 and 144 nM, respectively) that is more than 100-fold selective over other histone methyltransferases and non-epigenetic targets. A-196 has been shown to inhibit the di- and tri-methylation of lysine 20 of histone H4 (H4K20me) in multiple cell lines with IC50 values less than 1 μM. For more information on A-196 please visit the Structural Genomics Consortium (SGC). The negative control, SGC2043 (A-197), for A-196 is also available exclusively through the SGC. You can submit a request to receive the negative control here.

• SKU: CAY18317-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 18317-10
• Package Unit: 10 mg
• Quantity Unit: STK