A 419259 (GMP), CAS 364042-47-7

Product Description: A 419259 GMP is the GMP grade A 419259 (HY-15764), inducing cell apoptosis. GMP-grade small molecules can be used as auxiliary reagents in cell therapy. A 419259 (RK-20449) is a broad-spectrum pyrrole-pyrimidine inhibitor targeting Src, Lck, and Lyn with IC50s of 9 nM, [1][2].

Formula: C29H34N6O

References: [1]Wilson MB, et al. Selective pyrrolo-pyrimidine inhibitors reveal a necessary role for Src family kinases in Bcr-Abl signal transduction and oncogenesis. Oncogene. 2002 Nov 21;21(53):8075-88./[2]Zhang X, et al. Src-family tyrosine kinase activities are essential for differentiation of human embryonic stem cells. Stem Cell Res. 2014 Nov;13(3 Pt A):379-89.

CAS Number: 364042-47-7

Molecular Weight: 482.62

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Apoptosis;Src

• SKU: MEXHY-15764G-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-15764G-0
• Package Unit: Get quote
• Quantity Unit: STK