α-Amyrin, CAS 638-95-9

Formulation: A solid

Formal Name: (3β)-urs-12-en-3-ol

Purity: ≥95%

Formula Markup: C30H50O

Formula Weight: 426,7

Shelf life (days): 1460

CAS Number: 638-95-9

Notes: α-Amyrin is a triterpenoid that has been found in B. copallifera and has diverse biological activities.{52302,52304,50814,65871} It inhibits HIV-1 reverse transcriptase (IC50 = 3.3 µM).{52302} α-Amyrin inhibits the proliferation of B16 2F2 melanoma cells and LPS-induced nitric oxide (NO) production in RAW 264.7 macrophages (IC50s = 50 and 8.98 µM, respectively).{52304,50814} It reduces myeloperoxidase (MPO) activity, indicating a decrease in polymorphonuclear leukocyte (PMN) infiltration, and ear edema induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) in mice (ID50s = 0.45 and 0.31 mg/ear, respectively).{65871}

• SKU: CAY29831-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 29831-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK