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Biological Activity: Aliskiren is one of the most potent renin inhibitors with an IC50 value of 0.6 nM.
CAS Number: 173399-03-6
Description: Aliskiren Hydrochloride is an orally active, synthetic nonpeptide Renin inhibitor that has been shown to work as an antihypertensive.
Format: A crystalline solid
Purity: ≥95% by HPLC
Solubility: Soluble in methanol and chloroform.
Storage Stability: Store at or below -20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.
Biosafety Level: Not applicable (BSL-1)
References: 1. Wood, JM, et al., Biochem Biophys Res Commun. 2003 Sep 5;308(4):698-705.
2. Gradman, AH, et al., Circulation. 2005 Mar 1;111(8):1012-8.