ARQ 531, CAS 2095393-15-8

Formulation: A solid

Formal Name: 1,5-anhydro-2-[[5-(2-chloro-4-phenoxybenzoyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]-2,3,4-trideoxy-D-erythro-hexitol

Purity: ≥98%

Formula Markup: C25H23ClN4O4

Formula Weight: 478,9

Shelf life (days): 1460

CAS Number: 2095393-15-8

Notes: ARQ 531 is an inhibitor of Bruton's tyrosine kinase (BTK; IC50 = 0.85 nM).{51664} It reduces the viability of, and inhibits BTK autophosphorylation in, OCI-AML-2 acute myeloid leukemia (AML) cells when used at concentrations of 0.3 and 1 µM.{51663} In vivo, ARQ 531 (75 mg/kg) reduces tumor growth in an SU-DHL-4 B cell lymphoma mouse xenograft model.{51664}

• SKU: CAY30165-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 30165-5
• Package Unit: 5 mg
• Quantity Unit: STK