Formulation: A solid
Formal Name: 2-(3,4-dimethoxyphenyl)-5-hydroxy-3,6,7-trimethoxy-4H-1-benzopyran-4-one
Purity: ≥98%
Formula Markup: C20H20O8
Formula Weight: 388,4
Shelf life (days): 1460
CAS Number: 479-90-3
Notes: Artemitin is a flavonoid that has been found in A. annua and has diverse biological activities.{67668,67669,57215,67670,67671} It scavenges peroxyl radicals in a cell-free assay in a concentration-dependent manner.{67668} Artemitin inhibits 5-lipoxygenase (5-LO) with an IC50 value of 54.6 µM.{67669} It is active against P. falciparum (IC50 = 26 µM).{57215} Artemitin is cytotoxic to HL-60 leukemia cells (IC50 = 30.98 µM).{67670} In vivo, artemitin (0.75 mg/kg) decreases mean arterial blood pressure in normotensive rats, as well as reduces angiotensin I-induced, but not angiotensin II-induced, increases in mean arterial blood pressure in rats.{67671}
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