Atractylodin, CAS 55290-63-6

Formulation: A solid

Formal Name: 2-(1E,7E)-1,7-nonadiene-3,5-diyn-1-yl-furan

Purity: ≥98%

Formula Markup: C13H10O

Formula Weight: 182,2

Shelf life (days): 1460

CAS Number: 55290-63-6

Notes: Atractylodin is a polyethylene alkyne that has been found in A. lancea and has diverse biological activities.{60836,60837,60839,60840} It inhibits N-acylethanolamine acid amidase (NAAA; IC50 = 2.81 µM for the human enzyme) and increases levels of the endocannabinoids palmitoyl ethanolamide (Item No. 90350) and oleoyl ethanolamide (Item No. 90265) in LPS-stimulated BV-2 microglial cells when used at a concentration of 10 µM.{60836} Atractylodin is cytotoxic to CL-6 and HuCC-T1 cholangiocarcinoma cells (IC50s = 41.66 and 38.78 µM, respectively).{60837} Atractylodin (10 mg/kg) increases the gastric emptying rate in mice, an effect that can be blocked by the growth hormone secretagogue receptor (GHS-R) antagonist (D-Lys3)-GHRP-6 (Item No. 36862).{60839} It decreases pulmonary edema in a mouse model of LPS-induced acute lung injury when administered at doses of 40 and 80 mg/kg.{60840}

• SKU: CAY35033-50
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 35033-50
• Green Labware: No
• Package Unit: 50 mg
• Quantity Unit: STK