Formulation: A solid
Formal Name: (βS,3R)-γ-oxo-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]-β-[3-(trifluoromethyl)phenyl]-1-pyrrolidinebutanoic acid
Purity: ≥98%
Formula Markup: C25H28F3N3O3
Formula Weight: 475,5
Shelf life (days): 1460
CAS Number: 2615912-33-7
Notes: αvβ5 Integrin-IN-1 is an inhibitor of αVβ5 integrin (IC50 = 0.0063 µM).{69641} It is selective for αVβ5 over αVβ1, αVβ3, αVβ6, and αVβ8 (IC50s = 2.51, 5.01, 50.1, and 50.1 µM, respectively). αvβ5 Integrin-IN-1 inhibits adhesion of αVβ5-expressing K562 cells to vitronectin-coated plates.