AZD 5597, CAS 924641-59-8

AZD 5597, CAS 924641-59-8
SKU
CAY38526-50
Packaging Unit
50 mg
Manufacturer
Cayman Chemical

Availability: loading...
Price is loading...
Formulation: A solid

Formal Name: [4-[[5-fluoro-4-[2-methyl-1-(1-methylethyl)-1H-imidazol-5-yl]-2-pyrimidinyl]amino]phenyl][(3S)-3-(methylamino)-1-pyrrolidinyl]-methanone

Purity: ≥98%

Formula Markup: C23H28FN7O

Formula Weight: 437,5

Shelf life (days): 1460

CAS Number: 924641-59-8

Notes: AZD 5597 is a cyclin-dependent kinase 1 (Cdk1) and Cdk2 inhibitor (IC50 = 0.002 µM for both).{69536} It inhibits LoVo cell proliferation (IC50 = 0.039 µM). In vivo, AZD 5597 (15 mg/kg) reduces tumor volume in an SW620 colon adenocarcinoma mouse xenograft model.
More Information
SKU CAY38526-50
Manufacturer Cayman Chemical
Manufacturer SKU 38526-50
Green Labware No
Package Unit 50 mg
Quantity Unit STK
Product information (PDF) Download
MSDS (PDF) Download